Serious signal problems in Milton Keynes has affected services in and out of Euston one of the capitals main transport hubs, Network Rail has reported.
No trains were leaving or arriving at Euston because of the incident, leaving passengers stranded.
The lines affected the West Coast route, came to a halt at 9.30am hours after Network Rail announced the system was up and running following engineering work over the bank holiday weekend.
A loss of power at Milton Keynes forced all Virgin Trains services to and from the North to start and finish at Rugby and Northampton.
Trains immediately began to stack up on the main routes from Scotland to London. There was a train shuttle service between Euston and Bletchley.
The East Coast main line came to a halt after the 6.45am Skipton to King's Cross train killed a person on the line at Grantham. Commuters coming into Waterloo main line station also suffered delays caused by a signal failure at Wimbledon.
NR had been carrying out weekend engineering work at Milton Keynes but a spokesman said it was not connected with the loss of power.
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